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A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces
Despite their importance in maintaining the integrity of all cellular pathways, the role of mutations on protein-protein interaction (PPI) interfaces as cancer drivers has not been systematically studied. Here we analyzed the mutation patterns of the PPI interfaces from 10,028 proteins in a pan-canc...
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| Vydáno v: | PLoS Comput Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4616621/ https://ncbi.nlm.nih.gov/pubmed/26485003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004518 |
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