Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering

Transposable elements are efficient DNA carriers and thus important tools for transgenesis and insertional mutagenesis. However, their poor target sequence specificity constitutes an important limitation for site-directed applications. The insertion sequence IS608 from Helicobacter pylori recognizes...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Morero, Natalia Rosalía, Zuliani, Cecilia, Kumar, Banushree, Bebel, Aleksandra, Okamoto, Sachi, Guynet, Catherine, Hickman, Alison Burgess, Chandler, Michael, Dyda, Fred, Barabas, Orsolya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934647/
https://ncbi.nlm.nih.gov/pubmed/29635476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky235
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