IS200/IS605 family single-strand transposition: mechanism of IS608 strand transfer

Transposase, TnpA, of the IS200/IS605 family member IS608, catalyses single-strand DNA transposition and is dimeric with hybrid catalytic sites composed of an HUH motif from one monomer and a catalytic Y127 present in an α-helix (αD) from the other (trans configuration). αD is attached to the main b...

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Detalhes bibliográficos
Main Authors: He, Susu, Guynet, Catherine, Siguier, Patricia, Hickman, Alison B., Dyda, Fred, Chandler, Mick, Ton-Hoang, Bao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597680/
https://ncbi.nlm.nih.gov/pubmed/23345619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt014
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