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Regulation of amino acid metabolism and α‐cell proliferation by glucagon

Both glucagon and glucagon‐like peptide‐1 (GLP‐1) are produced from proglucagon through proteolytic cleavage. Blocking glucagon action increases the circulating levels of glucagon and GLP‐1, reduces the blood glucose level, and induces the proliferation of islet α‐cells. Glucagon blockade also suppr...

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Bibliografiske detaljer
Udgivet i:J Diabetes Investig
Main Authors: Hayashi, Yoshitaka, Seino, Yusuke
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934249/
https://ncbi.nlm.nih.gov/pubmed/29314731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12797
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