Insulin and Glucagon Regulate Pancreatic α-Cell Proliferation

Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from pancreatic α cells: excessively high circulating levels of glucagon lead to excessive hepatic glucose outpu...

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Main Authors: Liu, Zhuo, Kim, Wook, Chen, Zhike, Shin, Yu-Kyong, Carlson, Olga D., Fiori, Jennifer L., Xin, Li, Napora, Joshua K., Short, Ryan, Odetunde, Juliana O., Lao, Qizong, Egan, Josephine M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026810/
https://ncbi.nlm.nih.gov/pubmed/21283589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016096
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