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Regulation of amino acid metabolism and α‐cell proliferation by glucagon
Both glucagon and glucagon‐like peptide‐1 (GLP‐1) are produced from proglucagon through proteolytic cleavage. Blocking glucagon action increases the circulating levels of glucagon and GLP‐1, reduces the blood glucose level, and induces the proliferation of islet α‐cells. Glucagon blockade also suppr...
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| Pubblicato in: | J Diabetes Investig |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934249/ https://ncbi.nlm.nih.gov/pubmed/29314731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12797 |
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