載入...
ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer
Although EZH2 enzymatic inhibitors have shown anti-tumor effects in EZH2-mutated lymphoma and ARID1A-mutated ovarian cancer, many cancers do not respond because EZH2 can promote cancer independently of its histone methyltransferase activity. Here we identify ZRANB1 as the EZH2 deubiquitinase. ZRANB1...
Na minha lista:
| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933875/ https://ncbi.nlm.nih.gov/pubmed/29669287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.078 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|