SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity

Dysregulation of YAP localization and activity is associated with pathological conditions such as cancer. Although activation of the Hippo phosphorylation cascade is known to cause cytoplasmic retention and inactivation of YAP, emerging evidence suggests that YAP can be regulated in a Hippo-independ...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yao, Fan, Zhou, Zhicheng, Kim, Jongchan, Hang, Qinglei, Xiao, Zhenna, Ton, Baochau N., Chang, Liang, Liu, Na, Zeng, Liyong, Wang, Wenqi, Wang, Yumeng, Zhang, Peijing, Hu, Xiaoyu, Su, Xiaohua, Liang, Han, Sun, Yutong, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995870/
https://ncbi.nlm.nih.gov/pubmed/29891922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04620-y
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