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Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis
Transforming growth factor-β1 (TGF-β1) is a major mediator of peritoneal fibrosis and reportedly affects expression of the H3K4 methyltransferase, SET7/9. SET7/9-induced H3K4 mono-methylation (H3K4me1) critically activates transcription of fibrosis-related genes. In this study, we examined the effec...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933785/ https://ncbi.nlm.nih.gov/pubmed/29723250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196844 |
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