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Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes

Chromosome mis-segregation leads to aneuploidy, a condition in which cells harbor an imbalanced chromosome number. Several lines of evidence strongly indicate that aneuploidy triggers genome instability, ultimately generating cells with complex karyotypes that arrest their proliferation. Isolation a...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Wang, Ruoxi W., MacDuffie, Emily, Santaguida, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933501/
https://ncbi.nlm.nih.gov/pubmed/29708530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57215
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