Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation

The transcription factor BTB and CNC homology 1 (Bach1) regulates genes involved in the oxidative stress response and cell-cycle progression. We have recently shown that Bach1 impairs cell proliferation and promotes apoptosis in cultured endothelial cells (ECs), but the underlying mechanisms are lar...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Xinhong, Liu, Junxu, Jiang, Li, Wei, Xiangxiang, Niu, Cong, Wang, Rui, Zhang, Jianyi, Meng, Dan, Yao, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789484/
https://ncbi.nlm.nih.gov/pubmed/27057283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6234043
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