Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

While the introduction of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator drugs has revolutionized care in Cystic Fibrosis (CF), the genotype-directed therapy model currently in use has several limitations. First, rare or understudied mutation groups are excluded from definitive...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Brewington, John J., Filbrandt, Erin T., LaRosa, Francis J., Moncivaiz, Jessica D., Ostmann, Alicia J., Strecker, Lauren M., Clancy, John P.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2018
Assuntos:
Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933499/
https://ncbi.nlm.nih.gov/pubmed/29708545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57492
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