Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model

OBJECTIVE: We seek to characterize the effect of progesterone metabolites on spontaneous and oxytocin-induced uterine contractility. STUDY DESIGN: Spontaneous contractility was studied in mouse uterine horns after treatment with progesterone, 2α-hydroxyprogesterone, 6β-hydroxyprogesterone (6β-OHP),...

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Bibliographic Details
Published in:Reprod Sci
Main Authors: Patil, Avinash S., Swamy, Geeta K., Murtha, Amy P., Heine, R. Phillips, Zheng, Xiaomei, Grotegut, Chad A.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933197/
https://ncbi.nlm.nih.gov/pubmed/26037300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719115589414
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