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β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration

Desensitization of the oxytocin receptor (OXTR) in the setting of prolonged oxytocin exposure may lead to dysfunctional labor, which increases the risk for cesarean delivery, and uterine atony, which may result in postpartum hemorrhage. The molecular mechanism for OXTR desensitization is through the...

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Detalhes bibliográficos
Main Authors: Grotegut, Chad A., Feng, Liping, Mao, Lan, Heine, R. Phillips, Murtha, Amy P., Rockman, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064008/
https://ncbi.nlm.nih.gov/pubmed/21139074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00390.2010
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