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Immunotherapy with CAR-Modified T Cells: Toxicities and Overcoming Strategies

T cells modified via chimeric antigen receptors (CARs) have emerged as a promising treatment modality. Unparalleled clinical efficacy recently demonstrated in refractory B-cell malignancy has brought this new form of adoptive immunotherapy to the center stage. Nonetheless, its current success has al...

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Detalles Bibliográficos
Publicado en:J Immunol Res
Main Authors: Sun, Shangjun, Hao, He, Yang, Ge, Zhang, Yi, Fu, Yang
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932485/
https://ncbi.nlm.nih.gov/pubmed/29850622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2386187
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