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Human GUCY2C-targeted chimeric antigen receptor (CAR)-expressing T cells eliminate colorectal cancer metastases

One major hurdle to the success of adoptive T-cell therapy is the identification of antigens that permit effective targeting of tumors in the absence of toxicities to essential organs. Previous work has demonstrated that T cells engineered to express chimeric antigen receptors (CAR-T cells) targetin...

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Bibliografski detalji
Izdano u:Cancer Immunol Res
Glavni autori: Magee, Michael S., Abraham, Tara S., Baybutt, Trevor R., Flickinger, John C., Ridge, Natalie A., Marszalowicz, Glen P., Prajapati, Priyanka, Hersperger, Adam R., Waldman, Scott A., Snook, Adam E.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932207/
https://ncbi.nlm.nih.gov/pubmed/29615399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0362
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