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Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer

Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass. Beside this primary effect, OVs can also stimulate the immune system. Tumors are an immuno-suppressive environment in...

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發表在:Front Immunol
Main Authors: Marelli, Giulia, Howells, Anwen, Lemoine, Nicholas R., Wang, Yaohe
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932159/
https://ncbi.nlm.nih.gov/pubmed/29755464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00866
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