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Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer

Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass. Beside this primary effect, OVs can also stimulate the immune system. Tumors are an immuno-suppressive environment in...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Marelli, Giulia, Howells, Anwen, Lemoine, Nicholas R., Wang, Yaohe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932159/
https://ncbi.nlm.nih.gov/pubmed/29755464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00866
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