Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer

Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass. Beside this primary effect, OVs can also stimulate the immune system. Tumors are an immuno-suppressive environment in...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Marelli, Giulia, Howells, Anwen, Lemoine, Nicholas R., Wang, Yaohe
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932159/
https://ncbi.nlm.nih.gov/pubmed/29755464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00866
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