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Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer

Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass. Beside this primary effect, OVs can also stimulate the immune system. Tumors are an immuno-suppressive environment in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Marelli, Giulia, Howells, Anwen, Lemoine, Nicholas R., Wang, Yaohe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932159/
https://ncbi.nlm.nih.gov/pubmed/29755464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00866
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