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FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts

Group 3 tumors account for 28% of medulloblastomas and have the worst prognosis. FTY720, an immunosuppressant currently approved for treatment of multiple sclerosis, has shown antitumor effects in several human cancer cell lines. We hypothesized that treatment with FTY720 (fingolimod) would decrease...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Garner, Evan F., Williams, Adele P., Stafman, Laura L., Aye, Jamie M., Mroczek-Musulman, Elizabeth, Moore, Blake P., Stewart, Jerry E., Friedman, Gregory K., Beierle, Elizabeth A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932040/
https://ncbi.nlm.nih.gov/pubmed/29720672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25263-5
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