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Inherent flexibility of CLIC6 revealed by crystallographic and solution studies

Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membranes and mediate ion conduction in vitro, suggesting multim...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ferofontov, Alisa, Strulovich, Roi, Marom, Milit, Giladi, Moshe, Haitin, Yoni
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931990/
https://ncbi.nlm.nih.gov/pubmed/29720717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25231-z
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