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Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

The nucleolus is the major site for synthesis of ribosomes, complex molecular machines that are responsible for protein synthesis. A wealth of research over the past 20 years has clearly indicated that both quantitative and qualitative alterations in ribosome biogenesis can drive the malignant pheno...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Lindström, Mikael S., Jurada, Deana, Bursac, Sladana, Orsolic, Ines, Bartek, Jiri, Volarevic, Sinisa
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931986/
https://ncbi.nlm.nih.gov/pubmed/29429989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0121-z
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