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Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

The nucleolus is the major site for synthesis of ribosomes, complex molecular machines that are responsible for protein synthesis. A wealth of research over the past 20 years has clearly indicated that both quantitative and qualitative alterations in ribosome biogenesis can drive the malignant pheno...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Lindström, Mikael S., Jurada, Deana, Bursac, Sladana, Orsolic, Ines, Bartek, Jiri, Volarevic, Sinisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931986/
https://ncbi.nlm.nih.gov/pubmed/29429989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0121-z
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