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Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

The nucleolus is the major site for synthesis of ribosomes, complex molecular machines that are responsible for protein synthesis. A wealth of research over the past 20 years has clearly indicated that both quantitative and qualitative alterations in ribosome biogenesis can drive the malignant pheno...

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Detalles Bibliográficos
Publicado en:Oncogene
Autores principales: Lindström, Mikael S., Jurada, Deana, Bursac, Sladana, Orsolic, Ines, Bartek, Jiri, Volarevic, Sinisa
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931986/
https://ncbi.nlm.nih.gov/pubmed/29429989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0121-z
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