The Anti-microbial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance

Commensal bacteria are critical for physiological functions in the gut and dysbiosis in the gut may cause diseases. Here we report that mice deficient in cathelin-related antimicrobial peptide (CRAMP) were defective in the development of colon mucosa and highly sensitive to dextran-sulfate-sodium (D...

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Publicado no:J Immunol
Main Authors: Yoshimura, Teizo, McLean, Mairi H., Dzutsev, Amiran K., Yao, Xiaohong, Chen, Keqiang, Huang, Jiaqiang, Gong, Wanghua, Zhou, Jiamin, Xiang, Yi, Badger, Jonathan, Ohuigin, Colm, Thovarai, Vishal, Tessarollo, Lino, Durum, Scott K., Trinchieri, Giorgio, Bian, Xiu-wu, Wang, Ji Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931736/
https://ncbi.nlm.nih.gov/pubmed/29440355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602073
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