Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

The cathelin‐related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation‐associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp (−/−) mice (also known as Camp (−/−) mice). However, the mechanistic basis for the role and the cellular so...

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Dettagli Bibliografici
Pubblicato in:J Pathol
Autori principali: Chen, Keqiang, Yoshimura, Teizo, Yao, Xiaohong, Gong, Wanghua, Huang, Jiaqiang, Dzutsev, Amiran K, McCulloch, John, O'hUigin, Colm, Bian, Xiu‐wu, Trinchieri, Giorgio, Wang, Ji Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2021
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898386/
https://ncbi.nlm.nih.gov/pubmed/33104252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5572
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