Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

The cathelin‐related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation‐associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp (−/−) mice (also known as Camp (−/−) mice). However, the mechanistic basis for the role and the cellular so...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Chen, Keqiang, Yoshimura, Teizo, Yao, Xiaohong, Gong, Wanghua, Huang, Jiaqiang, Dzutsev, Amiran K, McCulloch, John, O'hUigin, Colm, Bian, Xiu‐wu, Trinchieri, Giorgio, Wang, Ji Ming
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2021
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898386/
https://ncbi.nlm.nih.gov/pubmed/33104252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5572
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