Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

The cathelin‐related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation‐associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp (−/−) mice (also known as Camp (−/−) mice). However, the mechanistic basis for the role and the cellular so...

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Опубликовано в: :J Pathol
Главные авторы: Chen, Keqiang, Yoshimura, Teizo, Yao, Xiaohong, Gong, Wanghua, Huang, Jiaqiang, Dzutsev, Amiran K, McCulloch, John, O'hUigin, Colm, Bian, Xiu‐wu, Trinchieri, Giorgio, Wang, Ji Ming
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Ltd 2021
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Original Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898386/
https://ncbi.nlm.nih.gov/pubmed/33104252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5572
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