Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

The cathelin‐related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation‐associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp (−/−) mice (also known as Camp (−/−) mice). However, the mechanistic basis for the role and the cellular so...

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Bibliografski detalji
Izdano u:J Pathol
Glavni autori: Chen, Keqiang, Yoshimura, Teizo, Yao, Xiaohong, Gong, Wanghua, Huang, Jiaqiang, Dzutsev, Amiran K, McCulloch, John, O'hUigin, Colm, Bian, Xiu‐wu, Trinchieri, Giorgio, Wang, Ji Ming
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2021
Teme:
Original Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898386/
https://ncbi.nlm.nih.gov/pubmed/33104252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5572
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