SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties

BACKGROUND: Serine proteases are important virulence factors for many pathogens. Recently, we discovered a group of trypsin-like serine proteases with domain organization unique to flatworm parasites and containing a thrombospondin type 1 repeat (TSR-1). These proteases are recognized as antigens du...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Leontovyč, Adrian, Ulrychová, Lenka, O’Donoghue, Anthony J., Vondrášek, Jiří, Marešová, Lucie, Hubálek, Martin, Fajtová, Pavla, Chanová, Marta, Jiang, Zhenze, Craik, Charles S., Caffrey, Conor R., Mareš, Michael, Dvořák, Jan, Horn, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931690/
https://ncbi.nlm.nih.gov/pubmed/29677188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006446
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