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Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors

BACKGROUND: Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Fajtová, Pavla, Štefanić, Saša, Hradilek, Martin, Dvořák, Jan, Vondrášek, Jiří, Jílková, Adéla, Ulrychová, Lenka, McKerrow, James H., Caffrey, Conor R., Mareš, Michael, Horn, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454677/
https://ncbi.nlm.nih.gov/pubmed/26039195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003827
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