Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength

Cytochrome P450 oxidoreductase (POR) is the primary electron donor in eukaryotic cytochrome P450 (CYP) containing systems. A wealth of ensemble biophysical studies of Cytochrome P450 oxidoreductase (POR) has reported a binary model of the conformational equilibrium directing its catalytic efficiency...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Bavishi, Krutika, Li, Darui, Eiersholt, Stine, Hooley, Emma N., Petersen, Troels C., Møller, Birger Lindberg, Hatzakis, Nikos S., Laursen, Tomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931563/
https://ncbi.nlm.nih.gov/pubmed/29717147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24922-x
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