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Structure and Function of an NADPH-Cytochrome P450 Oxidoreductase in an Open Conformation Capable of Reducing Cytochrome P450

NADPH-cytochrome P450 oxidoreductase (CYPOR) catalyzes the transfer of electrons to all known microsomal cytochromes P450. A CYPOR variant, with a 4-amino acid deletion in the hinge connecting the FMN domain to the rest of the protein, has been crystallized in three remarkably extended conformations...

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Библиографические подробности
Главные авторы: Hamdane, Djemel, Xia, Chuanwu, Im, Sang-Choul, Zhang, Haoming, Kim, Jung-Ja P., Waskell, Lucy
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670143/
https://ncbi.nlm.nih.gov/pubmed/19171935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807868200
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