Pharmacometabolomic signature links simvastatin therapy and insulin resistance

INTRODUCTION: Statins, widely prescribed drugs for treatment of cardiovascular disease, inhibit the biosynthesis of low density lipoprotein cholesterol (LDL-C). Despite providing major benefits, sub populations of patients experience adverse effects, including muscle myopathy and development of type...

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Bibliografski detalji
Izdano u:Metabolomics
Glavni autori: Elbadawi-Sidhu, Mona, Baillie, Rebecca A., Zhu, Hongjie, Chen, Yii-Der Ida, Goodarzi, Mark O., Rotter, Jerome I., Krauss, Ronald M., Fiehn, Oliver, Kaddurah-Daouk, Rima
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931366/
https://ncbi.nlm.nih.gov/pubmed/29732238
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