Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation

BACKGROUND: Paeoniflorin, a polyphenolic compound derived from Radix Paeoniae Alba (Paeonia lactiflora), has exhibited anticancer activity in various human cancers, including glioblastoma. However, the mechanisms underlying the effects of this compound have not been fully elucidated. Toll-like recep...

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Vydáno v:Cancer Manag Res
Hlavní autoři: Wang, Zhaotao, Yu, Guoyong, Liu, Zhi, Zhu, Jianwei, Chen, Chen, Liu, Ru-en, Xu, Ruxiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931203/
https://ncbi.nlm.nih.gov/pubmed/29740218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S160292
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