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Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin–proteasome pathway
We investigated the underlying mechanism for the potent proapoptotic effect of paeoniflorin (PF) on human glioma cells in vitro, focusing on signal transducer and activator of transcription 3 (STAT3) signaling. Significant time- and dose-dependent apoptosis and inhibition of proliferation were obser...
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| Опубликовано в: : | Drug Des Devel Ther |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610779/ https://ncbi.nlm.nih.gov/pubmed/26508835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93912 |
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