Stability of the HTLV-1 glycoprotein 46 (gp46) gene in an endemic region of the Brazilian Amazon and the presence of a significant mutation (N93D) in symptomatic patients

BACKGROUND: The human T-lymphotropic virus type 1 (HTLV-1) affects 2–5 million people worldwide, and is associated with a number of degenerative and infectious diseases. The Envelope glycoproteins (gp) are highly conserved among the different HTLV-1 isolates, although nucleotide substitutions in the...

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Vydáno v:Virol J
Hlavní autoři: Socorro de Almeida Viana, Maria de Nazaré do, Santos Nobre, Akim Felipe, Costa Jr, Edivaldo, Silva, Ingrid Christiane, Pinheiro, Bruna Teles, Pereira, Cássia Cristine Costa, de Souza Canto Ferreira, Louise, de Almeida, Danilo Souza, de Araújo, Marcos William Leão, da Silva Borges, Mariza, da Costa, Carlos Araujo, Ishikawa, Edna Aoba Yassui, Ferrari, Stephen Francis, Silva de Sousa, Maísa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930498/
https://ncbi.nlm.nih.gov/pubmed/29716616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-018-0984-9
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