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The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression

Pseudomonas aeruginosa is internalized into multiple types of epithelial cell in vitro and in vivo and yet is often regarded as an exclusively extracellular pathogen. Paradoxically, ExoS, a type three secretion system (T3SS) effector, has antiphagocytic activities but is required for intracellular s...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Kroken, Abby R., Chen, Camille K., Evans, David J., Yahr, Timothy L., Fleiszig, Suzanne M. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930308/
https://ncbi.nlm.nih.gov/pubmed/29717012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00668-18
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