Translocon-Independent Intracellular Replication by Pseudomonas aeruginosa Requires the ADP-Ribosylation Domain of ExoS

Pseudomonas aeruginosa, a significant cause of human morbidity and mortality, uses a type 3 secretion system (T3SS) to inject effector toxins into host cells. We previously reported that P. aeruginosa uses ADP-ribosyltransferase (ADPr) activity of the T3SS effector ExoS for intracellular replication...

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Bibliographic Details
Main Authors: Hritonenko, Victoria, Evans, David J., Fleiszig, Suzanne M. J.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522771/
https://ncbi.nlm.nih.gov/pubmed/22981600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2012.08.007
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