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The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression

Pseudomonas aeruginosa is internalized into multiple types of epithelial cell in vitro and in vivo and yet is often regarded as an exclusively extracellular pathogen. Paradoxically, ExoS, a type three secretion system (T3SS) effector, has antiphagocytic activities but is required for intracellular s...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Kroken, Abby R., Chen, Camille K., Evans, David J., Yahr, Timothy L., Fleiszig, Suzanne M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930308/
https://ncbi.nlm.nih.gov/pubmed/29717012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00668-18
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