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Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure: Critical Importance of the Cardiosplenic Axis

RATIONALE: The role of mononuclear phagocytes in chronic heart failure (HF) is unknown. OBJECTIVE: Our aim was to delineate monocyte, macrophage, and dendritic cell trafficking in HF and define the contribution of the spleen to cardiac remodeling. METHODS AND RESULTS: We evaluated C57Bl/6 mice with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Circ Res
Hauptverfasser: Ismahil, Mohamed Ameen, Hamid, Tariq, Bansal, Shyam S., Patel, Bindiya, Kingery, Justin R., Prabhu, Sumanth D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928520/
https://ncbi.nlm.nih.gov/pubmed/24186967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301720
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