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Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging
The ability to directly image and quantify drug-target engagement and drug distribution with subcellular resolution in live cells and whole organisms is a prerequisite to establishing accurate models of the kinetics and dynamics of drug action. Such methods would thus have far-reaching applications...
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| Publicat a: | Nat Protoc |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5928516/ https://ncbi.nlm.nih.gov/pubmed/28686582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.043 |
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