The Selective Antagonism of Adenosine A(2B) Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in Vitro

Ischemia is a multifactorial pathology characterized by different events evolving in time. Immediately after the ischemic insult, primary brain damage is due to the massive increase of extracellular glutamate. Adenosine in the brain increases dramatically during ischemia in concentrations able to st...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Fusco, Irene, Ugolini, Filippo, Lana, Daniele, Coppi, Elisabetta, Dettori, Ilaria, Gaviano, Lisa, Nosi, Daniele, Cherchi, Federica, Pedata, Felicita, Giovannini, Maria G., Pugliese, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928446/
https://ncbi.nlm.nih.gov/pubmed/29740323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00399
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