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A(3) adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro

1. The role of adenosine A(3) receptor activation during ischaemia-like conditions produced by oxygen and glucose deprivation (OGD) was evaluated with extracellular recordings from the CA1 region of rat hippocampal slices. In all, 7 min of OGD evoked tissue anoxic depolarisation (AD, peak at ∼7 min...

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Detalhes bibliográficos
Main Authors: Pugliese, Anna Maria, Coppi, Elisabetta, Spalluto, Giampiero, Corradetti, Renato, Pedata, Felicita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616978/
https://ncbi.nlm.nih.gov/pubmed/16415905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706646
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