The Selective Antagonism of Adenosine A(2B) Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in Vitro

Ischemia is a multifactorial pathology characterized by different events evolving in time. Immediately after the ischemic insult, primary brain damage is due to the massive increase of extracellular glutamate. Adenosine in the brain increases dramatically during ischemia in concentrations able to st...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Fusco, Irene, Ugolini, Filippo, Lana, Daniele, Coppi, Elisabetta, Dettori, Ilaria, Gaviano, Lisa, Nosi, Daniele, Cherchi, Federica, Pedata, Felicita, Giovannini, Maria G., Pugliese, Anna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928446/
https://ncbi.nlm.nih.gov/pubmed/29740323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00399
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