Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue

Eicosanoids, including prostaglandins (PGs) and thromboxanes, are broadly bioactive lipid mediators and increase colon tumorigenesis possibly through chronic inflammatory mechanisms. Epidemiological and experimental data suggest that acetylsalicylic acid (ASA) helps prevent colorectal cancer (CRC),...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Gottschall, Heike, Schmöcker, Christoph, Hartmann, Dirk, Rohwer, Nadine, Rund, Katharina, Kutzner, Laura, Nolte, Fabian, Ostermann, Annika I., Schebb, Nils Helge, Weylandt, Karsten H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928440/
https://ncbi.nlm.nih.gov/pubmed/29444936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078725
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