Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue

Eicosanoids, including prostaglandins (PGs) and thromboxanes, are broadly bioactive lipid mediators and increase colon tumorigenesis possibly through chronic inflammatory mechanisms. Epidemiological and experimental data suggest that acetylsalicylic acid (ASA) helps prevent colorectal cancer (CRC),...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Gottschall, Heike, Schmöcker, Christoph, Hartmann, Dirk, Rohwer, Nadine, Rund, Katharina, Kutzner, Laura, Nolte, Fabian, Ostermann, Annika I., Schebb, Nils Helge, Weylandt, Karsten H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Patient-Oriented and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928440/
https://ncbi.nlm.nih.gov/pubmed/29444936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078725
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