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The Versatility of Framework Regions of Chicken V(H) and V(L) to Mutations

To identify the interchangeability of V(H) and V(L) framework region (FR) residues, we artificially introduced random mutations at all residue positions in a chicken monoclonal antibody, which has only one functional V(H) and V(λ) gene. When we classified the amino acids into 5 groups by their physi...

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Bibliografski detalji
Izdano u:Immune Netw
Glavni autori: Shin, Jung Won, Kim, Sang Il, Yoon, Aerin, Jin, Junyeong, Park, Hyung Bae, Kim, Hyori, Chung, Junho
Format: Artigo
Jezik:Inglês
Izdano: The Korean Association of Immunologists 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928418/
https://ncbi.nlm.nih.gov/pubmed/29732232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2018.18.e3
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