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The Versatility of Framework Regions of Chicken V(H) and V(L) to Mutations

To identify the interchangeability of V(H) and V(L) framework region (FR) residues, we artificially introduced random mutations at all residue positions in a chicken monoclonal antibody, which has only one functional V(H) and V(λ) gene. When we classified the amino acids into 5 groups by their physi...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Shin, Jung Won, Kim, Sang Il, Yoon, Aerin, Jin, Junyeong, Park, Hyung Bae, Kim, Hyori, Chung, Junho
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928418/
https://ncbi.nlm.nih.gov/pubmed/29732232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2018.18.e3
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