Bone marrow‐derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition

There is growing evidence to suggest that bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are key players in tumour stroma. Here, we investigated the cross‐talk between BM‐MSCs and osteosarcoma (OS) cells. We revealed a strong tropism of BM‐MSCs towards these tumour cells and identified monocyt...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Pietrovito, Laura, Leo, Angela, Gori, Valentina, Lulli, Matteo, Parri, Matteo, Becherucci, Valentina, Piccini, Luisa, Bambi, Franco, Taddei, Maria Letizia, Chiarugi, Paola
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928379/
https://ncbi.nlm.nih.gov/pubmed/29517849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12189
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