Bone marrow‐derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition

There is growing evidence to suggest that bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are key players in tumour stroma. Here, we investigated the cross‐talk between BM‐MSCs and osteosarcoma (OS) cells. We revealed a strong tropism of BM‐MSCs towards these tumour cells and identified monocyt...

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發表在:Mol Oncol
Main Authors: Pietrovito, Laura, Leo, Angela, Gori, Valentina, Lulli, Matteo, Parri, Matteo, Becherucci, Valentina, Piccini, Luisa, Bambi, Franco, Taddei, Maria Letizia, Chiarugi, Paola
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928379/
https://ncbi.nlm.nih.gov/pubmed/29517849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12189
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