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Bone marrow‐derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition

There is growing evidence to suggest that bone marrow‐derived mesenchymal stem cells (BM‐MSCs) are key players in tumour stroma. Here, we investigated the cross‐talk between BM‐MSCs and osteosarcoma (OS) cells. We revealed a strong tropism of BM‐MSCs towards these tumour cells and identified monocyt...

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Bibliografische gegevens
Gepubliceerd in:Mol Oncol
Hoofdauteurs: Pietrovito, Laura, Leo, Angela, Gori, Valentina, Lulli, Matteo, Parri, Matteo, Becherucci, Valentina, Piccini, Luisa, Bambi, Franco, Taddei, Maria Letizia, Chiarugi, Paola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928379/
https://ncbi.nlm.nih.gov/pubmed/29517849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12189
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