Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells

BACKGROUND: Cellular plasticity confers cancer cells the ability to adapt to microenvironmental changes, a fundamental requirement for tumour progression and metastasis. The epithelial to mesenchymal transition (EMT) is a transcriptional programme associated with increased cell motility and stemness...

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Main Authors: Taddei, Maria Letizia, Giannoni, Elisa, Morandi, Andrea, Ippolito, Luigi, Ramazzotti, Matteo, Callari, Maurizio, Gandellini, Paolo, Chiarugi, Paola
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022383/
https://ncbi.nlm.nih.gov/pubmed/24690323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-24
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