Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

Annexin A5 (AnxA5) is known to have anti-inflammatory and anti-apoptotic properties. Inflammation and apoptosis are key processes in post-ischemic cardiac remodeling. In this study, we investigated the effect of AnxA5 on left ventricular (LV) function and remodeling three weeks after myocardial isch...

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Publicado en:Sci Rep
Autores principales: de Jong, Rob C. M., Pluijmert, Niek J., de Vries, Margreet R., Pettersson, Knut, Atsma, Douwe E., Jukema, J. Wouter, Quax, Paul H. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928225/
https://ncbi.nlm.nih.gov/pubmed/29712962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25143-y
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