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Therapeutic effects of CSF1R-blocking antibodies in multiple myeloma
Our previous studies showed that macrophages (MФs), especially myeloma-associated MФs (MAMs) induce chemoresistance in human myeloma. Here we explored the potential of targeting MФs, by using colony-stimulating factor 1 receptor (CSF1R)-blocking mAbs, to treat myeloma. Our results showed that CSF1R...
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| Publicado no: | Leukemia |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927777/ https://ncbi.nlm.nih.gov/pubmed/28626216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.193 |
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